Author: news_poster
Posted: Wed Feb 08, 2012 3:00 am
In conclusion, depending on the speed of transfer between the plasma and the effect site as well as the participation of active metabolites, the time�course of the analgesic effects can be close to the plasma concentrations (alfentanil and derivates) or observed with a prolonged delay (codeine, buprenorphine, morphine). These PK/PD data can be used to better characterize the differences between opioids, and partly explain the important observed variability among opioids in experimental conditions and should be systematically evaluated during drug development to better predict their selection in specific clinical conditions. (Source: Basic and Clinical Pharmacology and Toxicology)
Source: MedWorm Query: Buprenorphine
MedWorm.com provides a medical RSS filtering service. Data from over 6000 medical RSS feeds is collected and output via different categories. This feed contains the latest items on MedWorm Query: Buprenorphine
