Author: news_poster
Posted: Tue Aug 30, 2011 2:00 am
The objective of the present work was to investigate the effects of buprenorphine administration on testicular tissue in mice.
Sexually mature male mice were randomly divided into five experimental groups (n = 5) and the following treatments were intraperitoneally administered for 21 days: Control male mice were given physiological
saline. Positive control group was injected with morphine (Mor, 20 mg/kg). Three other groups were given different doses of
buprenorphine including 0.15 mg/kg (B15), 0.30 mg/kg (B30), and 0.60 mg/kg (B60). Left testes were removed for histopathological
evaluations and intracardiac blood samples were taken for testosterone assay. Morphometrically, the mean of seminiferous tubules
diameter, spermatogonial cells diameter, sertoli c…
Source: MedWorm Query: Buprenorphine
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