Author: hatmaker510
Posted: Sun Jul 17, 2011 11:37 am
Yes, that’s true about bupe, there’s no tolerance building and no need to raise one’s dose to get the same effect. That’s what the ceiling effect is about. Anything above it and additional dosages don’t do anything….even no additional respiratory depression. That’s why you won’t hear about anyone dying from an overdose from suboxone alone, unless you’re talking about an opiate naive person and even then it usually will only make them sick. Usually it’s from a mixture of sub and something like a benzo.
The thing is, when it comes to pain, everyone is different and sub works a little differently. For example, multiple day dosing is needed as it’s pain properties only last about 4-6 hours. I usually take on average 12-16 mg per day. Now on a REALLY bad day or flare up, I’ll take 24, but I’ve never gone above that. Cravings are really individualized, too. That’s why some people take 4 mg and are fine at that dose (which is about the ceiling) and others need 16 mg – it’s whatever they need to prevent cravings. And that amount depends on their tolerance.
It can be very confusing. It took me a while to understand all of suboxone’s mechanisms, so to speak. And I learned most of it right here on the forum and from Dr. J (and my own research). So don’t feel bad if you don’t understand it all yet. Maybe someone else will come along and explain it differently. Donh is always really good at it. (Where have you been, Don?)
